PDB | 5svt Anomalous Cs+ signal reveals the site of Na+ ion entry to the channel pore of the human P2X3 ion channel through the extracellular fenestrations

Anomalous Cs+ signal reveals the site of Na+ ion entry to the channel pore of the human P2X3 ion channel through the extracellular fenestrations

label Keywords
membrane protein, ion channel, anomalous signal
event_note Published
10/16/2024
blur_on Resolution
3.794 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, SODIUM ION

Original publication

import_contacts Title
X-ray structures define human P2X3 receptor gating cycle and antagonist action.
import_contacts Journal
Nature 2016
import_contacts DOI
10.1038/nature19367
person Authors
Lu, W., Mansoor, S.E., Tajkhorshid, E., Gouaux, E., Shekhar, M., Oosterheert, W.

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