PDB | 5svk ATP-gated human P2X3 ion channel in the ATP-bound, open state

Crystal structure of the ATP-gated human P2X3 ion channel in the ATP-bound, open state

label Keywords
membrane protein, ion channel, open state
event_note Published
11/13/2024
blur_on Resolution
2.773 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ADENOSINE-5'-TRIPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-ETHANEDIOL, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID

Original publication

import_contacts Title
X-ray structures define human P2X3 receptor gating cycle and antagonist action.
import_contacts Journal
Nature 2016
import_contacts DOI
10.1038/nature19367
person Authors
Lu, W., Mansoor, S.E., Tajkhorshid, E., Gouaux, E., Shekhar, M., Oosterheert, W.

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