PDB | 5om4 Structure of the A2A-StaR2-bRIL562-Compound 4e complex at 1.86A obtained

Structure of the A2A-StaR2-bRIL562-Compound 4e complex at 1.86A obtained from in meso soaking experiments (24 hour soak).

label Keywords
g-protein coupled receptor, adenosine 2a receptor, 7 tm integral membrane protein, thermostabilizing mutations, membrane protein
event_note Published
11/06/2024
blur_on Resolution
2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol, SODIUM ION, CHOLESTEROL, OLEIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

Original publication

import_contacts Title
Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.
import_contacts Journal
Sci Rep 2018
import_contacts DOI
10.1038/s41598-017-18570-w
person Authors
Cheng, R.K.Y., Dore, A.S., Errey, J.C., Rucktooa, P., Marshall, F.H., Geng, T., Brown, G.A., Segala, E., Cooke, R.M.

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