PDB | 5nx2 Thermostabilised full-length GLP-1R
Crystal structure of thermostabilised full-length GLP-1R in complex with a truncated peptide agonist at 3.7 A resolution
label Keywords
7tm, gpcr, signalling protein, membrane protein
event_note Published
01/17/2024
blur_on Resolution
3.7 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, octyl 1-thio-beta-D-glucopyranoside
Original publication
import_contacts Title
Crystal structure of the GLP-1 receptor bound to a peptide agonist.
import_contacts Journal
Nature 2017
import_contacts DOI
10.1038/nature22800
person Authors
Weir, M., Fiez-Vandal, C., Bortolato, A., Jazayeri, A., Baig, A.H., Robertson, N.J., Dore, A.S., Kean, J., Congreve, M., Errey, J.C., Rappas, M., Marshall, F.H., Mason, J.S., Teobald, I., Brown, A.J.H., Cooke, R.M., Andrews, S.P.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Weir, M., Fiez-Vandal, C., Bortolato, A., Jazayeri, A., Baig, A.H., Robertson, N.J., Dore, A.S., Kean, J., Congreve, M., Errey, J.C., Rappas, M., Marshall, F.H., Mason, J.S., Teobald, I., Brown, A.J.H., Cooke, R.M., Andrews, S.P. , provided free of copyright via the Protein DataBank. View original data or read license terms.
