PDB | 5n2r Stabilized A2A adenosine receptor A2AR-StaR2-bRIL
Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with PSB36 at 2.8A resolution
label Keywords
g-protein-coupled receptor, integral thermostabilizing mutations, membrane protein
event_note Published
10/23/2024
blur_on Resolution
2.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
SODIUM ION, 1-butyl-3-[(~{E})-3-oxidanylprop-1-enyl]-8-[(1~{R},5~{S})-3-tricyclo[3.3.1.0^{3,7}]nonanyl]-7~{H}-purine-2,6-dione, CHOLESTEROL, OLEIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, D(-)-TARTARIC ACID
Original publication
import_contacts Title
Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity.
import_contacts Journal
Structure 2017
import_contacts DOI
10.1016/j.str.2017.06.012
person Authors
Cheng, R.K.Y., Fiez-Vandal, C., Deflorian, F., Dore, A.S., Errey, J.C., Marshall, F.H., Robertson, N., Segala, E., Cooke, R.M.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Cheng, R.K.Y., Fiez-Vandal, C., Deflorian, F., Dore, A.S., Errey, J.C., Marshall, F.H., Robertson, N., Segala, E., Cooke, R.M. , provided free of copyright via the Protein DataBank. View original data or read license terms.
