PDB | 5mt6 Structure of E.coli GlpG

Structure of E.coli GlpG in complex with peptide derived inhibitor Ac-RVRHA-phenylethyl-ketoamide

label Keywords
hydrolase, membrane protein, intramembrane protease
event_note Published
11/13/2024
blur_on Resolution
2.16 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
nonyl beta-D-glucopyranoside

Original publication

import_contacts Title
General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases.
import_contacts Journal
Cell Chem Biol 2017
import_contacts DOI
10.1016/j.chembiol.2017.09.007
person Authors
Johnson, D.C., Nguyen, M.T.N., Vinothkumar, K.R., Began, J., Stanchev, S., Verhelst, S.H.L., Svehlova, K., Skerle, J., Lepsik, M., Majer, P., Pachl, P., Ticha, A., Bachovchin, D.A., Strisovsky, K., Mikles, D.C.

Loading