PDB | 5mkf CryoEM Structure of Polycystin-2 in complex with calcium and lipids

cryoEM Structure of Polycystin-2 in complex with calcium and lipids

label Keywords
ca2+ signaling, cryoem, membrane protein structure, polycystin-2, trp channel, transport protein
event_note Published
07/02/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, PALMITIC ACID, 4-AMINO-5-CYCLOHEXYL-3-HYDROXY-PENTANOIC ACID, CALCIUM ION

Original publication

import_contacts Title
Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2.
import_contacts Journal
Nat. Struct. Mol. Biol. 2017
import_contacts DOI
10.1038/nsmb.3357
person Authors
Wilkes, M., Ziegler, C., Witzgall, R., Huiskonen, J.T., Rhinow, D., Richter, R.M., Kuhlbrandt, W., Ruppel, S., Grieben, M., Pike, A.C., Heinz, V., Joos, F., Madej, M.G., Kreuter, L., Carpenter, E.P., De Sanctis, S.

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