PDB | 5lwy Human adiponectin receptor 2

Revised crystal structure of the human adiponectin receptor 2 in complex with a C18 free fatty acid

label Keywords
progestin and adipoq receptor family, integral membrane protein, 7tm, ceramidase, membrane protein
event_note Published
10/23/2024
blur_on Resolution
2.4 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ZINC ION, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID, GLYCEROL

Original publication

import_contacts Title
Structural insights into adiponectin receptors suggest ceramidase activity.
import_contacts Journal
Nature 2017
import_contacts DOI
10.1038/nature21714
person Authors
Saied, E.M., Leyrat, C., Hoh, F., Arenz, C., Granier, S., Rochaix, P., Vasiliauskaite-Brooks, I., De Colibus, L., Fortier, M., Bechara, C., Sounier, R., Bellot, G.

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