PDB | 5lm4 Structure of the thermostalilized EAAT1 cryst-II mutant
Structure of the thermostalilized EAAT1 cryst-II mutant in complex with L-ASP and the allosteric inhibitor UCPH101
label Keywords
excitatory amino acid transporter 1, human glutamate transporter, slc1a3, ucph101, transport protein
event_note Published
01/10/2024
blur_on Resolution
3.1 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
SODIUM ION, ASPARTIC ACID, 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile
Original publication
import_contacts Title
Structure and allosteric inhibition of excitatory amino acid transporter 1.
import_contacts Journal
Nature 2017
import_contacts DOI
10.1038/nature22064
person Authors
Assal, R., Chamot-Rooke, J., Brier, S., Legrand, P., Cirri, E., Canul-Tec, J.C., Reyes, N.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Assal, R., Chamot-Rooke, J., Brier, S., Legrand, P., Cirri, E., Canul-Tec, J.C., Reyes, N. , provided free of copyright via the Protein DataBank. View original data or read license terms.
