PDB | 5kmh Structure of CavAb

Structure of CavAb in complex with Br-verapamil

label Keywords
voltage-gated calcium channel, transport protein
event_note Published
06/27/2016
blur_on Resolution
3.2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CALCIUM ION, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, (2~{R})-2-(2-bromophenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile

Original publication

import_contacts Title
Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
import_contacts Journal
Nature 2016
import_contacts DOI
10.1038/nature19102
person Authors
Scheuer, T., Pryde, D.C., Zheng, N., Tang, L., Swanson, T.M., El-Din, T.M., Catterall, W.A.

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