PDB | 5k0i Mpges1 bound to an inhibitor
mpges1 bound to an inhibitor
label Keywords
mpges1, inhibitor, pain, inflammation, isomerase-isomerase inhibitor complex
event_note Published
05/17/2016
blur_on Resolution
1.3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
1,5-anhydro-2,3,4-trideoxy-3-{[(4S)-3,3-dimethyl-1-(8-methylquinolin-2-yl)piperidine-4-carbonyl]amino}-D-erythro-hexitol, GLUTATHIONE, octyl beta-D-glucopyranoside, TETRAETHYLENE GLYCOL
Original publication
import_contacts Title
Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors.
import_contacts Journal
Bioorg.Med.Chem.Lett. 2016
import_contacts DOI
10.1016/j.bmcl.2016.08.023
person Authors
Norman, B.H., Yu, X.P., Sloan, A.V., Antonysamy, S., Warshawsky, A.M., Schiffler, M.A., Quimby, S.J., Gooding, K., Luz, J.G., York, J.S., Chandrasekhar, S., Bhattachar, S.N., Fretland, A.J., Navarro, A., Fisher, M.J., McGee, J.E., Hughes, N.E., Manninen, P.R., Kuklish, S.L., Harvey, A., Partridge, K.M.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Norman, B.H., Yu, X.P., Sloan, A.V., Antonysamy, S., Warshawsky, A.M., Schiffler, M.A., Quimby, S.J., Gooding, K., Luz, J.G., York, J.S., Chandrasekhar, S., Bhattachar, S.N., Fretland, A.J., Navarro, A., Fisher, M.J., McGee, J.E., Hughes, N.E., Manninen, P.R., Kuklish, S.L., Harvey, A., Partridge, K.M. , provided free of copyright via the Protein DataBank. View original data or read license terms.
