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      PDB | 5irx Structure of TRPV1

      Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc

      label Keywords
      trp, ion channel, nanodisc, vanilloid, lipid, transport protein
      event_note Published
      11/13/2024
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, resiniferatoxin, (2S)-2-(acetyloxy)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propyl pentanoate

      Original publication

      import_contacts Title
      TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
      import_contacts Journal
      Nature 2016
      import_contacts DOI
      10.1038/nature17964
      person Authors
      Julius, D., Cheng, Y., Gao, Y., Cao, E.

      Read article from Nature

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Julius, D., Cheng, Y., Gao, Y., Cao, E. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

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