PDB | 5hxc Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 20 mM Na+ and zero Ca2+

label Keywords
na+/ca2+ exchange, calcium signalling, membrane transporter, induced conformational change, membrane protein
event_note Published
01/30/2016
blur_on Resolution
2.101 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CALCIUM ION, SODIUM ION, PENTAETHYLENE GLYCOL, 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, PENTADECANE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

Original publication

import_contacts Title
Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger
import_contacts Journal
Nat.Struct.Mol.Biol. 2016
import_contacts DOI
10.1038/nsmb.3230
person Authors
Marinelli, F., Huang, Y., Liao, J., Lee, C., Faraldo-Gomez, J.D., Jiang, Y.

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