PDB | 5f5j E.coli GlpG Y205F mutant complexed

E.coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle

label Keywords
glpg, rhomboid, bicelle, aldehyde inhibitor, hydrolase-inhibitor complex, hydrolase-hydrolase inhibitor complex
event_note Published
07/10/2024
blur_on Resolution
2.4 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands

Original publication

import_contacts Title
Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
import_contacts Journal
Mol.Cell 2016
import_contacts DOI
10.1016/j.molcel.2015.12.022
person Authors
Cho, S., Dickey, S.W., Urban, S.

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