PDB | 5esg Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73E mutant complexed
Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73E mutant complexed with itraconazole
label Keywords
cyp51, oxidoreductase-oxidoreducatse inhibitor complex, mutation, oxidoreductase-oxidoreductase inhibitor complex
event_note Published
11/16/2015
blur_on Resolution
1.981 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, PROTOPORPHYRIN IX CONTAINING FE
Original publication
import_contacts Title
Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase.
import_contacts Journal
Antimicrob.Agents Chemother. 2018
import_contacts DOI
10.1128/AAC.02242-17
person Authors
Keniya, M.V., Monk, B.C., Sagatova, A.A., Tyndall, J.D.A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Keniya, M.V., Monk, B.C., Sagatova, A.A., Tyndall, J.D.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
