PDB | 5ese Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73R mutant complexed
Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73R mutant complexed with fluconazole
label Keywords
cyp51, oxidoreductase-oxidoreductase inhibitor complex, mutation, g73r
event_note Published
11/16/2015
blur_on Resolution
2.2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
PROTOPORPHYRIN IX CONTAINING FE, 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL
Original publication
import_contacts Title
Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase.
import_contacts Journal
Antimicrob.Agents Chemother. 2018
import_contacts DOI
10.1128/AAC.02242-17
person Authors
Keniya, M.V., Monk, B.C., Sagatova, A.A., Tyndall, J.D.A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Keniya, M.V., Monk, B.C., Sagatova, A.A., Tyndall, J.D.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.