PDB | 5eqh Human GLUT1 in complex with inhibitor (2~{S})-3-(2-bromophenyl)-2-[2-(4-methoxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide
Human GLUT1 in complex with inhibitor (2~{S})-3-(2-bromophenyl)-2-[2-(4-methoxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide
label Keywords
mfs transporter, glucose transporter, transport protein-inhibitor complex
event_note Published
11/12/2015
blur_on Resolution
2.99 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2~{S})-3-(2-bromophenyl)-2-[2-(4-methoxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide
Original publication
import_contacts Title
Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2016
import_contacts DOI
10.1073/pnas.1603735113
person Authors
Kapoor, K., Waight, A., Siebeneicher, H., Caboni, L., Heisler, I., Finer-Moore, J.S., Stroud, R.M., Muller, T., Pedersen, B.P., Bringmann, P., Hillig, R.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Kapoor, K., Waight, A., Siebeneicher, H., Caboni, L., Heisler, I., Finer-Moore, J.S., Stroud, R.M., Muller, T., Pedersen, B.P., Bringmann, P., Hillig, R.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
