PDB | 5ee7 Human glucagon receptor (GCGR)
Crystal structure of the human glucagon receptor (GCGR) in complex with the antagonist MK-0893
label Keywords
gpcr, signaling protein, 7tm
event_note Published
10/16/2024
blur_on Resolution
2.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
3-[[4-[(1~{S})-1-[3-[3,5-bis(chloranyl)phenyl]-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]phenyl]carbonylamino]propanoic acid, OLEIC ACID, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, L(+)-TARTARIC ACID
Original publication
import_contacts Title
Extra-helical binding site of a glucagon receptor antagonist.
import_contacts Journal
Nature 2016
import_contacts DOI
10.1038/nature17414
person Authors
Weir, M., Brown, A.J., Southall, S.M., Robertson, N.J., Dore, A.S., Teobald, I., Lamb, D., Errey, J.C., Bortolato, A., Marshall, F.H., Baig, A.H., Krishnamurthy, H., Jazayeri, A., Cooke, R.M., Koglin, M., Andrews, S.P.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Weir, M., Brown, A.J., Southall, S.M., Robertson, N.J., Dore, A.S., Teobald, I., Lamb, D., Errey, J.C., Bortolato, A., Marshall, F.H., Baig, A.H., Krishnamurthy, H., Jazayeri, A., Cooke, R.M., Koglin, M., Andrews, S.P. , provided free of copyright via the Protein DataBank. View original data or read license terms.
