PDB | 5dhh Nociceptin/orphanin FQ peptide receptor (NOP)
The crystal structure of nociceptin/orphanin FQ peptide receptor (NOP) in complex with SB-612111 (PSI Community Target)
label Keywords
nociceptin/orphanin fq peptide receptor, nop, orl-1, n/ofq, opioid receptor, g protein-coupled receptor, gpcr, membrane protein, lipidic cubic phase, bret, receptor-ligand conformational pair, structural genomics, psi-biology, gpcr network, signaling protein, psicnt-127
event_note Published
10/23/2024
blur_on Resolution
3.004 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
OLEIC ACID, (5S,7S)-7-{[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl}-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Original publication
import_contacts Title
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor.
import_contacts Journal
Structure 2015
import_contacts DOI
10.1016/j.str.2015.07.024
person Authors
Guerrini, R., Patel, N., Calo, G., Cherezov, V., Han, G.W., Katritch, V., Miller, R.L., Stevens, R.C., Trapella, C., Malfacini, D., Thompson, A.A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Guerrini, R., Patel, N., Calo, G., Cherezov, V., Han, G.W., Katritch, V., Miller, R.L., Stevens, R.C., Trapella, C., Malfacini, D., Thompson, A.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
