PDB | 5a8e Thermostabilised beta1-adrenoceptor
thermostabilised beta1-adrenoceptor with rationally designed inverse agonist 7-methylcyanopindolol bound
label Keywords
signaling protein, inverse agonist
event_note Published
10/23/2024
blur_on Resolution
2.4 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
SODIUM ION, 4-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-7-methyl-1H-indole-2-carbonitrile, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Original publication
import_contacts Title
Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound Beta1-Adrenergic Receptor.
import_contacts Journal
Mol.Pharmacol. 2015
import_contacts DOI
10.1124/MOL.115.101030
person Authors
Leslie, A., Warne, T., Tate, C., Congreve, M., Baker, J., Brown, G., Sato, T.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Leslie, A., Warne, T., Tate, C., Congreve, M., Baker, J., Brown, G., Sato, T. , provided free of copyright via the Protein DataBank. View original data or read license terms.
