PDB | 4ze1 Saccharomyces cerevisiae CYP51 Y140F mutant complexed
Saccharomyces cerevisiae CYP51 Y140F mutant complexed with posaconazole in the active site
label Keywords
cyp51, oxidoreductase-oxidoreductase inhibitor complex, resistance mutation
event_note Published
03/13/2024
blur_on Resolution
2.05 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
PROTOPORPHYRIN IX CONTAINING FE, POSACONAZOLE
Original publication
import_contacts Title
Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase.
import_contacts Journal
Sci Rep 2016
import_contacts DOI
10.1038/srep26213
person Authors
Tyndall, J.D., Wilson, R.K., Monk, B.C., Sagatova, A.A., Sabherwal, M., Keniya, M.V.
copyrightData provided by Research Collaboration for Structural Biology, Tyndall, J.D., Wilson, R.K., Monk, B.C., Sagatova, A.A., Sabherwal, M., Keniya, M.V. , provided free of copyright via the Protein DataBank. View original data or read license terms.
