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      PDB | 4ze0 Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140F mutant complexed

      Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140F mutant complexed with Voriconazole

      label Keywords
      cyp51, oxidoreductase-oxidoreducatse inhibitor complex, y140f, resistance mutation
      event_note Published
      03/13/2024
      blur_on Resolution
      2.2 Å
      filter_center_focus Method
      X-RAY DIFFRACTION
      add_circle Ligands
      PROTOPORPHYRIN IX CONTAINING FE, Voriconazole

      Original publication

      import_contacts Title
      Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase.
      import_contacts Journal
      Sci Rep 2016
      import_contacts DOI
      10.1038/srep26213
      person Authors
      Tyndall, J.D., Wilson, R.K., Monk, B.C., Sagatova, A.A., Sabherwal, M., Keniya, M.V.

      Read article from Sci Rep

      copyrightData provided by Research Collaboration for Structural Biology, Tyndall, J.D., Wilson, R.K., Monk, B.C., Sagatova, A.A., Sabherwal, M., Keniya, M.V. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

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