PDB | 4z90 ELIC bound with the anesthetic isoflurane in the resting state
ELIC bound with the anesthetic isoflurane in the resting state
label Keywords
elic, isoflurane, inhibition, anesthetics, resting state, transport protein
event_note Published
04/09/2015
blur_on Resolution
3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2R)-2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Original publication
import_contacts Title
Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC.
import_contacts Journal
Sci Rep 2015
import_contacts DOI
10.1038/srep13833
person Authors
Kinde, M.N., Arjunan, P., Tang, P., Cohen, A.E., Xu, Y., Wells, M.M., Chen, Q.
copyrightData provided by Research Collaboration for Structural Biology, Kinde, M.N., Arjunan, P., Tang, P., Cohen, A.E., Xu, Y., Wells, M.M., Chen, Q. , provided free of copyright via the Protein DataBank. View original data or read license terms.
