PDB | 4z36 Human Lysophosphatidic Acid Receptor 1
Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO-3080573
label Keywords
human lysophosphatidic acid receptor 1 (lpa1), g-protein coupled receptor (gpcr), membrane protein, antagonist, endogenous ligand, psi-biology, structural genomics, gpcr network, lipidic cubic phase (lcp), novel disulfide bond engineering, compound design, polypharmacology, lipid receptor, transport protein-inhibitor complex
event_note Published
11/13/2024
blur_on Resolution
2.9 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
1-(4-{[(2S,3R)-2-(2,3-dihydro-1H-inden-2-yloxy)-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]oxy}phenyl)cyclopropan ecarboxylic acid, (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate
Original publication
import_contacts Title
Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1.
import_contacts Journal
Cell 2015
import_contacts DOI
10.1016/j.cell.2015.06.002
person Authors
Chrencik, J.E., Griffith, M.T., Velasquez, J., Roth, C.B., Hanson, M.A., Nakade, S., Han, G.W., Kihara, Y., Kurata, H., Mileni, M., Terakado, M., Stevens, R.C., Rodgers, C., Asmar-Rovira, G., Mizuno, H., Warshaviak, D., Chun, J., Omi, R.
copyrightData provided by Research Collaboration for Structural Biology, Chrencik, J.E., Griffith, M.T., Velasquez, J., Roth, C.B., Hanson, M.A., Nakade, S., Han, G.W., Kihara, Y., Kurata, H., Mileni, M., Terakado, M., Stevens, R.C., Rodgers, C., Asmar-Rovira, G., Mizuno, H., Warshaviak, D., Chun, J., Omi, R. , provided free of copyright via the Protein DataBank. View original data or read license terms.
