PDB | 4yl0 Crystal Structures of mPGES-1 Inhibitor Complexes
Crystal Structures of mPGES-1 Inhibitor Complexes
label Keywords
inflammation, prostaglandin, isomerase-isomerase inhibitor complex
event_note Published
03/04/2015
blur_on Resolution
1.52 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-(9-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)benzene-1,3-dicarbonitrile, GLUTATHIONE, octyl beta-D-glucopyranoside, TETRAETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER
Original publication
import_contacts Title
Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics.
import_contacts Journal
J.Med.Chem. 2015
import_contacts DOI
10.1021/acs.jmedchem.5b00330
person Authors
Russell, M., Yu, X.P., Allison, D., Backer, R., Chang, S.S., Luz, J.G., Zhang, A., Chandrasekhar, S., Kuklish, S.L., Lee, M.R., Antonysamy, S., Condon, B., Fisher, M.J., Harvey, A., Sloan, A.V.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Russell, M., Yu, X.P., Allison, D., Backer, R., Chang, S.S., Luz, J.G., Zhang, A., Chandrasekhar, S., Kuklish, S.L., Lee, M.R., Antonysamy, S., Condon, B., Fisher, M.J., Harvey, A., Sloan, A.V. , provided free of copyright via the Protein DataBank. View original data or read license terms.
