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      PDB | 4xpt Drosophila dopamine transporter

      X-ray structure of Drosophila dopamine transporter with subsiteB mutations D121G/S426M and EL2 deletion of 162-201 in complex with substrate analogue 3,4 dichlorophen ethylamine

      label Keywords
      integral membrane protein, all-alpha helical antidepressant complex, transport protein-inhibitor complex, protein transport-inhibitor complex
      event_note Published
      10/09/2024
      blur_on Resolution
      3.36 Å
      filter_center_focus Method
      X-RAY DIFFRACTION
      add_circle Ligands
      CHOLESTEROL HEMISUCCINATE, 2-(3,4-dichlorophenyl)ethanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, CHLORIDE ION, SODIUM ION

      Original publication

      import_contacts Title
      Neurotransmitter and psychostimulant recognition by the dopamine transporter.
      import_contacts Journal
      Nature 2015
      import_contacts DOI
      10.1038/nature14431
      person Authors
      Gouaux, E., Penmatsa, A., Wang, K.H.

      Read article from Nature

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Gouaux, E., Penmatsa, A., Wang, K.H. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline4xpt_default_dppc

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