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      PDB | 4xpf Drosophila dopamine transporter

      X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to RTI-55

      label Keywords
      all alpha-helical integral membrane protein, transport protein-inhibitor complex
      event_note Published
      10/30/2024
      blur_on Resolution
      3.273 Å
      filter_center_focus Method
      X-RAY DIFFRACTION
      add_circle Ligands
      DECYL-BETA-D-MALTOPYRANOSIDE, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, methyl (1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, CHOLESTEROL, SODIUM ION, CHLORIDE ION

      Original publication

      import_contacts Title
      Neurotransmitter and psychostimulant recognition by the dopamine transporter.
      import_contacts Journal
      Nature 2015
      import_contacts DOI
      10.1038/nature14431
      person Authors
      Gouaux, E., Penmatsa, A., Wang, K.H.

      Read article from Nature

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Gouaux, E., Penmatsa, A., Wang, K.H. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline4xpf_default_dppc

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