PDB | 4xdj Human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2)
Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2)
label Keywords
transport protein, outward rectification, membrane protein, k2p, structural genomics, structural genomics consortium, sgc
event_note Published
10/16/2024
blur_on Resolution
3.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
POTASSIUM ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, TRIDECANE
Original publication
import_contacts Title
K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.
import_contacts Journal
Science 2015
import_contacts DOI
10.1126/science.1261512
person Authors
McClenaghan, C., Sansom, M.S., Ruda, G.F., Mukhopadhyay, S., Burgess-Brown, N.A., Grieben, M., Pike, A.C., Mackenzie, A., Dong, Y.Y., Tucker, S.J., Aryal, P., Dong, L., Quigley, A., Clausen, M.V., Carpenter, E.P., Goubin, S., Brennan, P.E., Cao, L.
copyrightData provided by Research Collaboration for Structural Biology, McClenaghan, C., Sansom, M.S., Ruda, G.F., Mukhopadhyay, S., Burgess-Brown, N.A., Grieben, M., Pike, A.C., Mackenzie, A., Dong, Y.Y., Tucker, S.J., Aryal, P., Dong, L., Quigley, A., Clausen, M.V., Carpenter, E.P., Goubin, S., Brennan, P.E., Cao, L. , provided free of copyright via the Protein DataBank. View original data or read license terms.
