PDB | 4twf Pentameric ligand gated ion channel

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine

label Keywords
elic, lgic, cys-loop, channel, memantine, pore blocker, transport protein
event_note Published
06/30/2014
blur_on Resolution
3.901 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
Bromomemantine

Original publication

import_contacts Title
The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine.
import_contacts Journal
Structure 2014
import_contacts DOI
10.1016/j.str.2014.07.013
person Authors
Alqazzaz, M., Thompson, A.J., Price, K., Han, L., Villalgordo, J.M., Debaveye, S., Spurny, R., Lummis, S.C., Ulens, C., Lynch, J.W., Tresadern, G.

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