PDB | 4twf Pentameric ligand gated ion channel
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine
label Keywords
elic, lgic, cys-loop, channel, memantine, pore blocker, transport protein
event_note Published
06/30/2014
blur_on Resolution
3.901 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
Bromomemantine
Original publication
import_contacts Title
The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine.
import_contacts Journal
Structure 2014
import_contacts DOI
10.1016/j.str.2014.07.013
person Authors
Alqazzaz, M., Thompson, A.J., Price, K., Han, L., Villalgordo, J.M., Debaveye, S., Spurny, R., Lummis, S.C., Ulens, C., Lynch, J.W., Tresadern, G.
copyrightData provided by Research Collaboration for Structural Biology, Alqazzaz, M., Thompson, A.J., Price, K., Han, L., Villalgordo, J.M., Debaveye, S., Spurny, R., Lummis, S.C., Ulens, C., Lynch, J.W., Tresadern, G. , provided free of copyright via the Protein DataBank. View original data or read license terms.