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      PDB | 4ro2 CNG mimicking NaK-ETPP mutant cocrystallized

      Crystal Structure of CNG mimicking NaK-ETPP mutant cocrystallized with Methylammonium

      label Keywords
      alpha helical membrane protein, ion channel, transport protein
      event_note Published
      10/27/2014
      blur_on Resolution
      2.7 Å
      filter_center_focus Method
      X-RAY DIFFRACTION
      add_circle Ligands
      methylammonium ion, GLYCINE, (4S)-2-METHYL-2,4-PENTANEDIOL

      Original publication

      import_contacts Title
      A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
      import_contacts Journal
      Proc.Natl.Acad.Sci.USA 2015
      import_contacts DOI
      10.1073/pnas.1503334112
      person Authors
      Laio, A., De March, M., Onesti, S., Torre, V., Marchesi, A., Arcangeletti, M., Demitri, N., Bisha, I., Magistrato, A., Rodriguez, A., Napolitano, L.M., Mazzolini, M.

      Read article from Proc.Natl.Acad.Sci.USA

      copyrightData provided by Research Collaboration for Structural Biology, Laio, A., De March, M., Onesti, S., Torre, V., Marchesi, A., Arcangeletti, M., Demitri, N., Bisha, I., Magistrato, A., Rodriguez, A., Napolitano, L.M., Mazzolini, M. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline4ro2_default_dppc

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