PDB | 4r7c CNG mimicking NaK-ETPP mutant cocrystallized
Crystal Structure of CNG mimicking NaK-ETPP mutant cocrystallized with DiMethylammonium
label Keywords
alpha-helical membrane protein, nak-chimera channel in complex with dima+, transport protein
event_note Published
08/27/2014
blur_on Resolution
2.3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
GLYCINE, (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYLAMINE
Original publication
import_contacts Title
A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2015
import_contacts DOI
10.1073/pnas.1503334112
person Authors
Laio, A., De March, M., Onesti, S., Torre, V., Marchesi, A., Arcangeletti, M., Demitri, N., Bisha, I., Magistrato, A., Rodriguez, A., Napolitano, L.M., Mazzolini, M.
copyrightData provided by Research Collaboration for Structural Biology, Laio, A., De March, M., Onesti, S., Torre, V., Marchesi, A., Arcangeletti, M., Demitri, N., Bisha, I., Magistrato, A., Rodriguez, A., Napolitano, L.M., Mazzolini, M. , provided free of copyright via the Protein DataBank. View original data or read license terms.
