PDB | 4pxz Crystal structure of P2Y12 receptor in complex with 2MeSADP
Crystal structure of P2Y12 receptor in complex with 2MeSADP
label Keywords
purinergic receptor p2y12, agonist-bound, g-protein coupled receptor (gpcr), membrane protein, signaling protein-agonist complex, psi-biology, gpcr network, structural genomics, signaling membrane protein, gpcr, platelet activation, membrane
event_note Published
11/20/2024
blur_on Resolution
2.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER
Original publication
import_contacts Title
Agonist-bound structure of the human P2Y12 receptor
import_contacts Journal
Nature 2014
import_contacts DOI
10.1038/nature13288
person Authors
Zhang, W., Cherezov, V., Gao, Z.G., Jiang, H., Zhao, Q., Han, G.W., Li, T., Ma, L., Yang, H., Katritch, V., Muller, C.E., Wu, B., Jacobson, K.A., Zhang, K., Paoletta, S., Zhang, J., Zhang, D., Stevens, R.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Zhang, W., Cherezov, V., Gao, Z.G., Jiang, H., Zhao, Q., Han, G.W., Li, T., Ma, L., Yang, H., Katritch, V., Muller, C.E., Wu, B., Jacobson, K.A., Zhang, K., Paoletta, S., Zhang, J., Zhang, D., Stevens, R.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
