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PDB | 4pxf Active G-protein-coupled receptor opsin

Crystal structure of the active G-protein-coupled receptor opsin in complex with the finger-loop peptide derived from the full-length arrestin-1

label Keywords
retinal protein, photoreceptor, g-protein coupled receptor, phosphoprotein, photoreceptor protein, sensory transduction, transducer, transmembrane, vision, signaling protein, visual arrestin, desensitisation of the visual transduction cascade, binding to acticated and phosphorylated rhodopsin, rhodopsin, opsin
event_note Published
10/09/2024
blur_on Resolution
2.75 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
octyl beta-D-glucopyranoside, PALMITIC ACID, SULFATE ION, ACETATE ION

Original publication

import_contacts Title
Crystal structure of a common GPCR-binding interface for G protein and arrestin.
import_contacts Journal
Nat Commun 2014
import_contacts DOI
10.1038/ncomms5801
person Authors
Rose, A., Elgeti, M., von Stetten, D., Szczepek, M., Kazmin, R., Sommer, M.E., Beyriere, F., Bartl, F.J., Hofmann, K.P., Scheerer, P., Heck, M., Hildebrand, P.W.

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