PDB | 4pd4 Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action
Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action
label Keywords
cytochrome bc1 complex, membrane protein complex, antimalarial drug, inhibitor, oxidoreductase-inhibitor complex
event_note Published
11/20/2024
blur_on Resolution
3.04 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
UNDECYL-MALTOSIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, FE2/S2 (INORGANIC) CLUSTER
Original publication
import_contacts Title
Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action.
import_contacts Journal
Nat Commun 2014
import_contacts DOI
10.1038/ncomms5029
person Authors
Kao, W.C., Birth, D., Hunte, C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Kao, W.C., Birth, D., Hunte, C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
