PDB | 4oo9 Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain
Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant
label Keywords
7tm, receptor, g-protein, cysteine-s-acetamide, membrane protein
event_note Published
01/31/2014
blur_on Resolution
2.6 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
OLEIC ACID, Mavoglurant, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Original publication
import_contacts Title
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.
import_contacts Journal
Nature 2014
import_contacts DOI
10.1038/nature13396
person Authors
Weir, M., Wiggin, G.R., Khan, S., Patel, J.C., Serrano-Vega, M., Dore, A.S., Bennett, K., Cooke, R.M., Okrasa, K., Marshall, F.H., Tehan, B., Jazayeri, A., Errey, J.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Weir, M., Wiggin, G.R., Khan, S., Patel, J.C., Serrano-Vega, M., Dore, A.S., Bennett, K., Cooke, R.M., Okrasa, K., Marshall, F.H., Tehan, B., Jazayeri, A., Errey, J.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.