PDB | 4ntj Structure of the human P2Y12 receptor
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
label Keywords
human p2y12 receptor, gpcr network, membrane protein, lipidic cubic phase, antithrombotic drug, gpcr, psi-biology, structural genomics, signaling protein, membrane
event_note Published
11/06/2024
blur_on Resolution
2.62 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ethyl 6-{4-[(benzylsulfonyl)carbamoyl]piperidin-1-yl}-5-cyano-2-methylpyridine-3-carboxylate, CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Original publication
import_contacts Title
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
import_contacts Journal
Nature 2014
import_contacts DOI
10.1038/nature13083
person Authors
Zhang, W., Moss, S.M., Zhao, Q., Cherezov, V., Yang, H., Lu, W., Jiang, H., Kiselev, E., Han, G.W., Fenalti, G., Zhu, L., Gao, Z.-G., Katritch, V., Muller, C.E., Wu, B., Jacobson, K.A., Zhang, K., Paoletta, S., Zhang, J., Zhang, D., Stevens, R.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Zhang, W., Moss, S.M., Zhao, Q., Cherezov, V., Yang, H., Lu, W., Jiang, H., Kiselev, E., Han, G.W., Fenalti, G., Zhu, L., Gao, Z.-G., Katritch, V., Muller, C.E., Wu, B., Jacobson, K.A., Zhang, K., Paoletta, S., Zhang, J., Zhang, D., Stevens, R.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
