PDB | 4mbs CCR5 Chemokine Receptor
Crystal Structure of the CCR5 Chemokine Receptor
label Keywords
human ccr5 chemokine receptor, anti-hiv agent, novel protein engineering, gpcr network, membrane protein, psi-biology, structural genomics, seven transmembrane helices, g protein-coupled receptor, membrane, signaling protein
event_note Published
11/20/2024
blur_on Resolution
2.71 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
4,4-difluoro-N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl}-1-phenylpropyl]cyclohexanecarboxamide, ZINC ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Original publication
import_contacts Title
Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex.
import_contacts Journal
Science 2013
import_contacts DOI
10.1126/science.1241475
person Authors
Chen, Z., Zhu, Y., Tan, Q., Cherezov, V., Kufareva, I., Jiang, H., Xie, X., Han, G.W., Li, T., Ma, L., Fenalti, G., Yang, H., Wu, B., Li, J., Zhao, Q., Liu, H., Zhang, W., Stevens, R.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chen, Z., Zhu, Y., Tan, Q., Cherezov, V., Kufareva, I., Jiang, H., Xie, X., Han, G.W., Li, T., Ma, L., Fenalti, G., Yang, H., Wu, B., Li, J., Zhao, Q., Liu, H., Zhang, W., Stevens, R.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
