PDB | 4kfm G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2)

Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with the beta-gamma G protein subunits

label Keywords
metal transport, ion channel, potassium channel, inward rectification, sodium binding, pip2 binding, g protein binding
event_note Published
11/06/2024
blur_on Resolution
3.45 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, POTASSIUM ION, SODIUM ION, DODECYL-BETA-D-MALTOSIDE

Original publication

import_contacts Title
X-ray structure of the mammalian GIRK2-beta gamma G-protein complex.
import_contacts Journal
Nature 2013
import_contacts DOI
10.1038/nature12241
person Authors
Whorton, M.R., MacKinnon, R.

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