PDB | 4ib4 Chimeric protein of 5-HT2B-BRIL
Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine
label Keywords
ergotamine, novel protein engineering, gpcr network, membrane protein, psi-biology, structural genomics, gpcr, signaling protein, electron transport, gpcr dock
event_note Published
11/06/2024
blur_on Resolution
2.7 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
Ergotamine, PALMITIC ACID, CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID, DI(HYDROXYETHYL)ETHER
Original publication
import_contacts Title
Structural features for functional selectivity at serotonin receptors.
import_contacts Journal
Science 2013
import_contacts DOI
10.1126/science.1232808
person Authors
Chu, M., Cherezov, V., Vardy, E., Wang, C., Han, G.W., Xu, H.E., Roth, B.L., Katritch, V., Siu, F.Y., Stevens, R.C., McCorvy, J.D., Wacker, D., Huang, X.P., Jiang, Y., Liu, W.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chu, M., Cherezov, V., Vardy, E., Wang, C., Han, G.W., Xu, H.E., Roth, B.L., Katritch, V., Siu, F.Y., Stevens, R.C., McCorvy, J.D., Wacker, D., Huang, X.P., Jiang, Y., Liu, W. , provided free of copyright via the Protein DataBank. View original data or read license terms.
