PDB | 4eiy Chimeric protein of A2aAR-BRIL
Crystal structure of the chimeric protein of A2aAR-BRIL in complex with ZM241385 at 1.8A resolution
label Keywords
novel protein engineering, gpcr network, psi-biology, structural genomics, membrane protein, gpcr
event_note Published
11/06/2024
blur_on Resolution
1.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, CHOLESTEROL, OLEIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER
Original publication
import_contacts Title
Structural basis for allosteric regulation of GPCRs by sodium ions.
import_contacts Journal
Science 2012
import_contacts DOI
10.1126/science.1219218
person Authors
Chun, E., Roth, C.B., Chubukov, P., Cherezov, V., Heitman, L.H., Han, G.W., Katritch, V., Liu, W., Xu, F., Stevens, R.C., Thompson, A.A., IJzerman, A.P.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chun, E., Roth, C.B., Chubukov, P., Cherezov, V., Heitman, L.H., Han, G.W., Katritch, V., Liu, W., Xu, F., Stevens, R.C., Thompson, A.A., IJzerman, A.P. , provided free of copyright via the Protein DataBank. View original data or read license terms.
