PDB | 4dkl Mu-opioid receptor bound to a morphinan antagonist
Crystal structure of the mu-opioid receptor bound to a morphinan antagonist
label Keywords
g-protein coupled receptor, 7 transmembrane receptor, signaling protein-antagonist complex
event_note Published
11/27/2024
blur_on Resolution
2.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
methyl 4-{[(5beta,6alpha)-17-(cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-yl]amino}-4-oxobutanoate, SULFATE ION, CHOLESTEROL, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate, PENTAETHYLENE GLYCOL, CHLORIDE ION
Original publication
import_contacts Title
Crystal structure of the {mu}-opioid receptor bound to a morphinan antagonist.
import_contacts Journal
Nature 2012
import_contacts DOI
10.1038/nature10954
person Authors
Thian, F.S., Weis, W.I., Kobilka, B.K., Granier, S., Mathiesen, J.M., Kruse, A.C., Manglik, A., Sunahara, R.K., Kobilka, T.S., Pardo, L.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Thian, F.S., Weis, W.I., Kobilka, B.K., Granier, S., Mathiesen, J.M., Kruse, A.C., Manglik, A., Sunahara, R.K., Kobilka, T.S., Pardo, L. , provided free of copyright via the Protein DataBank. View original data or read license terms.
