PDB | 4djh Structure of the human kappa opioid receptor

Structure of the human kappa opioid receptor in complex with JDTic

label Keywords
jdtic, gpcr newtork, psi-biology, kor, hkor, kop, structural genomics, protein structure initiative, gpcr network, g-protein coupled receptor, gpcr, 7tm, kappa opioid receptor, dynorphin, membrane protein, transmembrane, hormone receptor, hydrolase, hormone receptor-antagonist complex
event_note Published
11/27/2024
blur_on Resolution
2.9 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, CITRIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER

Original publication

import_contacts Title
tructure of the human kappa-opioid receptor in complex with JDTic
import_contacts Journal
Nature 2012
import_contacts DOI
10.1038/nature10939
person Authors
Vardy, E., Carroll, F.I., Roth, B.L., Stevens, R.C., Cherezov, V., Han, G.W., Mileni, M., Katritch, V., Wu, H., Thompson, A.A., Mosier, P.D., Wacker, D., Huang, X.P., Mascarella, S.W., Liu, W., Westkaemper, R.B.

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