PDB | 4bvn Ultra-thermostable beta1-adrenoceptor

Ultra-thermostable beta1-adrenoceptor with cyanopindolol bound

label Keywords
signaling protein
event_note Published
10/23/2024
blur_on Resolution
2.1 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
SODIUM ION, 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

Original publication

import_contacts Title
The 2.1 A Resolution Structure of Cyanopindolol-Bound Beta1- Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor.
import_contacts Journal
Plos One 2014
import_contacts DOI
10.1371/JOURNAL.PONE.0092727
person Authors
Warne, T., Edwards, P.C., Leslie, A.G.W., Tate, C.G., Nehme, R., Miller-Gallacher, J.L., Schertler, G.F.X.

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