PDB | 4a97 Pentameric ligand gated ion channel
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with zopiclone
label Keywords
transport protein, cys-loop receptor, gaba-a receptor, benzodiazepine
event_note Published
11/24/2011
blur_on Resolution
3.343 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(5R)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
Original publication
import_contacts Title
Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2012
import_contacts DOI
10.1073/PNAS.1208208109
person Authors
Sieghart, W., Price, K., Corringer, P., Verheij, M., Legrand, P., Ramerstorfer, J., Lummis, S.C.R., Nury, H., Spurny, R., De Esch, I.J.P., Ulens, C., Ernst, M., Dougherty, D.A., Bertrand, D., Brams, M., Bertrand, S.
copyrightData provided by Research Collaboration for Structural Biology, Sieghart, W., Price, K., Corringer, P., Verheij, M., Legrand, P., Ramerstorfer, J., Lummis, S.C.R., Nury, H., Spurny, R., De Esch, I.J.P., Ulens, C., Ernst, M., Dougherty, D.A., Bertrand, D., Brams, M., Bertrand, S. , provided free of copyright via the Protein DataBank. View original data or read license terms.
