PDB | 4a4m Light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant

Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)

label Keywords
signaling protein, g-protein, g-protein-coupled receptors, signal tansduction, visual system, metarhodopsin-ii
event_note Published
10/16/2024
blur_on Resolution
3.3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
RETINAL, ACETATE ION, octyl beta-D-glucopyranoside, PALMITIC ACID

Original publication

import_contacts Title
Stabilized G Protein Binding Site in the Structure of Constitutively Active Metarhodopsin-II.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2012
import_contacts DOI
10.1073/PNAS.1114089108
person Authors
Nickle, B., Deupi, X., Edwards, P., Standfuss, J., Oprian, D., Schertler, G., Singhal, A.

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