PDB | 3zpq Thermostabilised turkey beta1 adrenergic receptor
Thermostabilised turkey beta1 adrenergic receptor with 4-(piperazin-1- yl)-1H-indole bound (compound 19)
label Keywords
membrane protein, gpcr, fragment screening, aryl piperazine, structure based drug design
event_note Published
11/13/2024
blur_on Resolution
2.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHOLESTEROL HEMISUCCINATE, HEGA-10, 4-(PIPERAZIN-1-YL)-1H-INDOLE, SODIUM ION
Original publication
import_contacts Title
Biophysical Fragment Screening of the Beta1-Adrenergic Receptor: Identification of High Affinity Aryl Piperazine Leads Using Structure-Based Drug Design.
import_contacts Journal
J.Med.Chem. 2013
import_contacts DOI
10.1021/JM400140Q
person Authors
Warne, T., Errey, J., Congreve, M., Marshall, F.H., Tehan, B., Dore, A., Christopher, J., Brown, J., Tate, C.G., Koglin, M., Rich, R.L., Myszka, D.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Warne, T., Errey, J., Congreve, M., Marshall, F.H., Tehan, B., Dore, A., Christopher, J., Brown, J., Tate, C.G., Koglin, M., Rich, R.L., Myszka, D. , provided free of copyright via the Protein DataBank. View original data or read license terms.
