PDB | 3vga Human adenosine A2A receptor

Crystal structure of human adenosine A2A receptor with an allosteric inverse-agonist antibody at 3.1 A resolution

label Keywords
7 transmembrane receptor, signal transduction, signaling protein
event_note Published
10/30/2024
blur_on Resolution
3.1 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol

Original publication

import_contacts Title
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
import_contacts Journal
Nature 2012
import_contacts DOI
10.1038/nature10750
person Authors
Cameron, A.D., Nomura, N., Kobayashi, T., Nakada-Nakura, Y., Kusano-Arai, O., Iwata, S., Yurugi-Kobayashi, T., Iwanari, H., Ikeda-Suno, C., Shimamura, T., Weyand, S., Arakawa, T., Murata, T., Hino, T., Hamakubo, T.

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