PDB | 3uzc Thermostabilised Adenosine A2A receptor
Thermostabilised Adenosine A2A receptor in complex with 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
label Keywords
7tm, gpcr, g-protein, membrane protein, signaling protein
event_note Published
10/30/2024
blur_on Resolution
3.341 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
Original publication
import_contacts Title
Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design
import_contacts Journal
J.Med.Chem. 2012
import_contacts DOI
10.1021/jm201376w
person Authors
Weir, M., Dore, A.S., Congreve, M., Zhukov, A., Langmead, C.J., Hurrell, E., Marshall, F.H., Ng, I.W., Mason, J.S., Hollenstein, K., Tehan, B., Andrews, S.P.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Weir, M., Dore, A.S., Congreve, M., Zhukov, A., Langmead, C.J., Hurrell, E., Marshall, F.H., Ng, I.W., Mason, J.S., Hollenstein, K., Tehan, B., Andrews, S.P. , provided free of copyright via the Protein DataBank. View original data or read license terms.
