PDB | 3qs6 LeuT mutant F259V,I359Q bound to sodium and L-tryptophan

Crystal structure of LeuT mutant F259V,I359Q bound to sodium and L-tryptophan

label Keywords
nss, neurotransmitter transporter, leut-fold, sodium-coupled secondary transporter, sodium and amino acid binding, membrane, transport protein
event_note Published
02/19/2011
blur_on Resolution
2.801 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
TRYPTOPHAN, SODIUM ION, octyl beta-D-glucopyranoside

Original publication

import_contacts Title
Insights into transport mechanism from LeuT engineered to transport tryptophan.
import_contacts Journal
Embo J. 2012
import_contacts DOI
10.1038/emboj.2011.353
person Authors
Gouaux, E., Piscitelli, C.L.

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