PDB | 3pds Irreversible Agonist-Beta2 Adrenoceptor Complex

Irreversible Agonist-Beta2 Adrenoceptor Complex

label Keywords
gpcr, signaling, beta adrenergic agonist, fusion protein, membrane protein-hydrolase complex
event_note Published
10/30/2024
blur_on Resolution
3.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one, CHOLESTEROL, SULFATE ION

Original publication

import_contacts Title
Structure and function of an irreversible agonist-beta(2) adrenoceptor complex
import_contacts Journal
Nature 2011
import_contacts DOI
10.1038/nature09665
person Authors
Weis, W.I., Gellman, S.H., Kobilka, B.K., Chae, P.S., Lyons, J.A., Zhang, C., Rasmussen, S.G.F., Holl, R., Sunahara, R.K., Choi, H.J., Arlow, D.H., Shaw, D.E., Aragao, D., Rosenbaum, D.M., Gmeiner, P., Caffrey, M., Dror, R.O., Devree, B.T.

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